F362-1728 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide

F362-1728 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide
F362-1728 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F362-1728
1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F362-1728

Molecular Formula

C22H23FN4O2S (C22 H23 FN4 O2 S)

Compound Name

1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(5-methylfuran-2-yl)methyl]piperidine-4-carboxamide

SMILES

Cc1ccc(CNC(C(CC2)CCN2c(cc2)nnc2Sc2cc(F)ccc2)=O)o1

InChI

InChI=1S/C22H23FN4O2S/c1-15-5-6-18(29-15)14-24-22(28)16-9-11-27(12-10-16)20-7-8-21(26-25-20)30-19-4-2-3-17(23)13-19/h2-8,13,16H,9-12,14H2,1H3,(H,24,28)

InChI Key

AVPIPXPSFVIMDT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119213

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.169

Distribution Coefficient, logD

4.169

Water Solubility, LogSw

-4.11

Polar Surface Area

55.663

Acid Dissociation Constant (pKa)

12.38

Base Dissociation Constant (pKb)

3.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

F362-1728 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with F362-1728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F362-1728?
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What is the minimum amount of F362-1728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F362-1728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F362-1728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F362-1728 available by request