F362-1753 Screening compound: ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate

F362-1753 Screening compound: ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate
F362-1753 Screening compound: ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound F362-1753
ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F362-1753

Molecular Formula

C24H29FN4O3S (C24 H29 FN4 O3 S)

Compound Name

ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate

IUPAC name

ethyl 1-(1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}piperidine-4-carbonyl)piperidine-3-carboxylate

SMILES

CCOC(C(CCC1)CN1C(C(CC1)CCN1c(cc1)nnc1Sc1cc(F)ccc1)=O)=O

InChI

InChI=1S/C24H29FN4O3S/c1-2-32-24(31)18-5-4-12-29(16-18)23(30)17-10-13-28(14-11-17)21-8-9-22(27-26-21)33-20-7-3-6-19(25)15-20/h3,6-9,15,17-18H,2,4-5,10-14,16H2,1H3/t18-/m0/s1

InChI Key

VPIGXUOWEIIWQJ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27119216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.953

Distribution Coefficient, logD

3.953

Water Solubility, LogSw

-3.88

Polar Surface Area

61.322

Acid Dissociation Constant (pKa)

22.59

Base Dissociation Constant (pKb)

8.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

F362-1753 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F362-1753 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F362-1753?
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What is the minimum amount of F362-1753 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F362-1753
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F362-1753
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F362-1753 available by request