F363-1446 Screening compound: 1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide

F363-1446 Screening compound: 1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide
F363-1446 Screening compound: 1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F363-1446
1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F363-1446

Molecular Formula

C19H23BrN4O2S (C19 H23 BrN4 O2 S)

Compound Name

1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide

IUPAC name

1-{6-[(4-bromophenyl)sulfanyl]pyridazin-3-yl}-N-(2-hydroxypropyl)piperidine-3-carboxamide

SMILES

CC(CNC(C(CCC1)CN1c(cc1)nnc1Sc(cc1)ccc1Br)=O)O

InChI

InChI=1S/C19H23BrN4O2S/c1-13(25)11-21-19(26)14-3-2-10-24(12-14)17-8-9-18(23-22-17)27-16-6-4-15(20)5-7-16/h4-9,13-14,25H,2-3,10-12H2,1H3,(H,21,26)

InChI Key

JHALMLZKWUPZHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.131

Distribution Coefficient, logD

3.131

Water Solubility, LogSw

-3.20

Polar Surface Area

65.083

Acid Dissociation Constant (pKa)

14.87

Base Dissociation Constant (pKb)

4.63

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

42.10

F363-1446 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with F363-1446 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F363-1446?
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What is the minimum amount of F363-1446 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F363-1446
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F363-1446
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F363-1446 available by request