F365-0379 Screening compound: 8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F365-0379 Screening compound: 8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F365-0379 Screening compound: 8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F365-0379
8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F365-0379

Molecular Formula

C24H24ClFN6O3 (C24 H24 ClFN6 O3)

Compound Name

8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

8-chloro-2-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4-propyl-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

CCCN(C(N1c2c3ccc(Cl)c2)=NN(CC(N(CC2)CCN2c(cccc2)c2F)=O)C1=O)C3=O

InChI

InChI=1S/C24H24ClFN6O3/c1-2-9-30-22(34)17-8-7-16(25)14-20(17)32-23(30)27-31(24(32)35)15-21(33)29-12-10-28(11-13-29)19-6-4-3-5-18(19)26/h3-8,14H,2,9-13,15H2,1H3

InChI Key

LNDQSOXJNZBVSH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119471

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.166

Distribution Coefficient, logD

3.166

Water Solubility, LogSw

-3.58

Polar Surface Area

67.537

Acid Dissociation Constant (pKa)

19.28

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F365-0379 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F365-0379 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F365-0379?
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What is the minimum amount of F365-0379 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F365-0379
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F365-0379
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F365-0379 available by request