F366-0135 Screening compound: 4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0135 Screening compound: 4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0135 Screening compound: 4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0135
4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0135

Molecular Formula

C24H17ClN4O3 (C24 H17 ClN4 O3)

Compound Name

4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

4-benzyl-2-[2-(3-chlorophenyl)-2-oxoethyl]-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

O=C(CN(C(N1c2c3cccc2)=O)N=C1N(Cc1ccccc1)C3=O)c1cccc(Cl)c1

InChI

InChI=1S/C24H17ClN4O3/c25-18-10-6-9-17(13-18)21(30)15-28-24(32)29-20-12-5-4-11-19(20)22(31)27(23(29)26-28)14-16-7-2-1-3-8-16/h1-13H,14-15H2

InChI Key

DCPUAKHOEXOKHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119593

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.88

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.406

Distribution Coefficient, logD

4.406

Water Solubility, LogSw

-4.63

Polar Surface Area

61.182

Acid Dissociation Constant (pKa)

16.11

Base Dissociation Constant (pKb)

-1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

F366-0135 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F366-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0135?
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What is the minimum amount of F366-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0135 available by request