F366-0137 Screening compound: 4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0137 Screening compound: 4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0137 Screening compound: 4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0137
4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0137

Molecular Formula

C27H21N5O3 (C27 H21 N5 O3)

Compound Name

4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

4-benzyl-2-[2-(2-methyl-1H-indol-3-yl)-2-oxoethyl]-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

Cc1c(C(CN(C(N2c3c4cccc3)=O)N=C2N(Cc2ccccc2)C4=O)=O)c(cccc2)c2[nH]1

InChI

InChI=1S/C27H21N5O3/c1-17-24(19-11-5-7-13-21(19)28-17)23(33)16-31-27(35)32-22-14-8-6-12-20(22)25(34)30(26(32)29-31)15-18-9-3-2-4-10-18/h2-14,28H,15-16H2,1H3

InChI Key

BLVBEMNIVZAIQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119594

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.033

Distribution Coefficient, logD

4.033

Water Solubility, LogSw

-4.45

Polar Surface Area

71.108

Acid Dissociation Constant (pKa)

15.97

Base Dissociation Constant (pKb)

-1.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F366-0137 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F366-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0137?
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What is the minimum amount of F366-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0137 available by request