F366-0218 Screening compound: 2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0218 Screening compound: 2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0218 Screening compound: 2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0218
2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0218

Molecular Formula

C25H19FN4O3 (C25 H19 FN4 O3)

Compound Name

2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

2-[2-(4-fluorophenyl)-2-oxoethyl]-4-(2-phenylethyl)-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

O=C(CN(C(N1c2c3cccc2)=O)N=C1N(CCc1ccccc1)C3=O)c(cc1)ccc1F

InChI

InChI=1S/C25H19FN4O3/c26-19-12-10-18(11-13-19)22(31)16-29-25(33)30-21-9-5-4-8-20(21)23(32)28(24(30)27-29)15-14-17-6-2-1-3-7-17/h1-13H,14-16H2

InChI Key

CQWZICNMYBSCNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119665

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.636

Distribution Coefficient, logD

3.636

Water Solubility, LogSw

-4.03

Polar Surface Area

61.161

Acid Dissociation Constant (pKa)

15.95

Base Dissociation Constant (pKb)

-2.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

F366-0218 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F366-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0218?
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What is the minimum amount of F366-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0218 available by request