F366-0399 Screening compound: 8-chloro-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0399 Screening compound: 8-chloro-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0399 Screening compound: 8-chloro-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0399
8-chloro-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0399

Molecular Formula

C22H21ClN4O3 (C22 H21 ClN4 O3)

Compound Name

8-chloro-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

8-chloro-2-[2-(24-dimethylphenyl)-2-oxoethyl]-4-propyl-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

CCCN(C(N1c2c3ccc(Cl)c2)=NN(CC(c2c(C)cc(C)cc2)=O)C1=O)C3=O

InChI

InChI=1S/C22H21ClN4O3/c1-4-9-25-20(29)17-8-6-15(23)11-18(17)27-21(25)24-26(22(27)30)12-19(28)16-7-5-13(2)10-14(16)3/h5-8,10-11H,4,9,12H2,1-3H3

InChI Key

UCSDCSLOMCOTQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.89

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.361

Distribution Coefficient, logD

4.361

Water Solubility, LogSw

-4.52

Polar Surface Area

61.432

Acid Dissociation Constant (pKa)

16.34

Base Dissociation Constant (pKb)

-2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

F366-0399 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Inflammatory Library (24602 compounds)

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • Others
  • GPCR
Agro:
  • Agro
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F366-0399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0399?
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What is the minimum amount of F366-0399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0399 available by request