F366-0418 Screening compound: 8-chloro-2-[(2,5-dimethylphenyl)methyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

F366-0418 Screening compound: 8-chloro-2-[(2,5-dimethylphenyl)methyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione
F366-0418 Screening compound: 8-chloro-2-[(2,5-dimethylphenyl)methyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F366-0418
8-chloro-2-[(2,5-dimethylphenyl)methyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F366-0418

Molecular Formula

C21H21ClN4O2 (C21 H21 ClN4 O2)

Compound Name

8-chloro-2-[(2,5-dimethylphenyl)methyl]-4-propyl-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-1,5-dione

IUPAC name

8-chloro-2-[(25-dimethylphenyl)methyl]-4-propyl-1H2H4H5H-[124]triazolo[43-a]quinazoline-15-dione

SMILES

CCCN(C(N1c2c3ccc(Cl)c2)=NN(Cc2c(C)ccc(C)c2)C1=O)C3=O

InChI

InChI=1S/C21H21ClN4O2/c1-4-9-24-19(27)17-8-7-16(22)11-18(17)26-20(24)23-25(21(26)28)12-15-10-13(2)5-6-14(15)3/h5-8,10-11H,4,9,12H2,1-3H3

InChI Key

MMBMMLPKNPRTGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119710

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.999

Distribution Coefficient, logD

4.999

Water Solubility, LogSw

-4.89

Polar Surface Area

48.185

Acid Dissociation Constant (pKa)

23.45

Base Dissociation Constant (pKb)

0.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

F366-0418 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F366-0418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F366-0418?
Check Price and Availability of F366-0418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F366-0418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F366-0418
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F366-0418
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F366-0418 available by request