F367-0134 Screening compound: N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

F367-0134 Screening compound: N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide
F367-0134 Screening compound: N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F367-0134
N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F367-0134

Molecular Formula

C24H27N5O3S (C24 H27 N5 O3 S)

Compound Name

N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

IUPAC name

N-(2-methylphenyl)-2-({5-oxo-4-[3-(propan-2-yloxy)propyl]-4H5H-[124]triazolo[43-a]quinazolin-1-yl}sulfanyl)acetamide

SMILES

CC(C)OCCCN(c(n1-c2c3cccc2)nnc1SCC(Nc1c(C)cccc1)=O)C3=O

InChI

InChI=1S/C24H27N5O3S/c1-16(2)32-14-8-13-28-22(31)18-10-5-7-12-20(18)29-23(28)26-27-24(29)33-15-21(30)25-19-11-6-4-9-17(19)3/h4-7,9-12,16H,8,13-15H2,1-3H3,(H,25,30)

InChI Key

QQPLYIRFXKOQDH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119750

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.756

Distribution Coefficient, logD

2.756

Water Solubility, LogSw

-3.36

Polar Surface Area

69.215

Acid Dissociation Constant (pKa)

12.65

Base Dissociation Constant (pKb)

0.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F367-0134 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F367-0134 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F367-0134?
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What is the minimum amount of F367-0134 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F367-0134
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F367-0134
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F367-0134 available by request