F367-0217 Screening compound: N-(2,4-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

F367-0217 Screening compound: N-(2,4-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide
F367-0217 Screening compound: N-(2,4-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F367-0217
N-(2,4-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F367-0217

Molecular Formula

C24H16F3N5O2S (C24 H16 F3 N5 O2 S)

Compound Name

N-(2,4-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}sulfanyl)acetamide

IUPAC name

N-(24-difluorophenyl)-2-({4-[(4-fluorophenyl)methyl]-5-oxo-4H5H-[124]triazolo[43-a]quinazolin-1-yl}sulfanyl)acetamide

SMILES

O=C(CSc(n1-c2c3cccc2)nnc1N(Cc(cc1)ccc1F)C3=O)Nc(ccc(F)c1)c1F

InChI

InChI=1S/C24H16F3N5O2S/c25-15-7-5-14(6-8-15)12-31-22(34)17-3-1-2-4-20(17)32-23(31)29-30-24(32)35-13-21(33)28-19-10-9-16(26)11-18(19)27/h1-11H,12-13H2,(H,28,33)

InChI Key

MPJLKBUTFDTQFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14951830

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.840

Distribution Coefficient, logD

3.833

Water Solubility, LogSw

-4.11

Polar Surface Area

61.764

Acid Dissociation Constant (pKa)

9.21

Base Dissociation Constant (pKb)

-1.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

F367-0217 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Immunological Library (6760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system

References: we are preparing a list of scientific research reports with F367-0217 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F367-0217?
Check Price and Availability of F367-0217, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F367-0217 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F367-0217
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F367-0217
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F367-0217 available by request