F373-0018 Screening compound: 1-(3,4-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidin-2-one

F373-0018 Screening compound: 1-(3,4-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidin-2-one
F373-0018 Screening compound: 1-(3,4-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F373-0018
1-(3,4-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F373-0018

Molecular Formula

C24H26N4O2 (C24 H26 N4 O2)

Compound Name

1-(3,4-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-1,2,4-oxadiazol-5-yl}pyrrolidin-2-one

IUPAC name

1-(34-dimethylphenyl)-4-{3-[4-(pyrrolidin-1-yl)phenyl]-124-oxadiazol-5-yl}pyrrolidin-2-one

SMILES

Cc(cc1)c(C)cc1N(CC(C1)c2nc(-c(cc3)ccc3N3CCCC3)no2)C1=O

InChI

InChI=1S/C24H26N4O2/c1-16-5-8-21(13-17(16)2)28-15-19(14-22(28)29)24-25-23(26-30-24)18-6-9-20(10-7-18)27-11-3-4-12-27/h5-10,13,19H,3-4,11-12,14-15H2,1-2H3/t19-/m1/s1

InChI Key

IEMXTNYTZJJVTA-LJQANCHMSA-N

MDL Number (MFCD)

MFCD27120584

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.774

Distribution Coefficient, logD

5.774

Water Solubility, LogSw

-5.37

Polar Surface Area

52.213

Acid Dissociation Constant (pKa)

11.87

Base Dissociation Constant (pKb)

1.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

F373-0018 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F373-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F373-0018?
Check Price and Availability of F373-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F373-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F373-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F373-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F373-0018 available by request