F373-0500 Screening compound: 3-({3-[4-(MORPHOLIN-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}METHYL)-1H-INDOLE

F373-0500 Screening compound: 3-({3-[4-(MORPHOLIN-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}METHYL)-1H-INDOLE
F373-0500 Screening compound: 3-({3-[4-(MORPHOLIN-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}METHYL)-1H-INDOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound F373-0500
3-({3-[4-(MORPHOLIN-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}METHYL)-1H-INDOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F373-0500

Molecular Formula

C21H20N4O2 (C21 H20 N4 O2)

Compound Name

3-({3-[4-(MORPHOLIN-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}METHYL)-1H-INDOLE

IUPAC name

3-({3-[4-(morpholin-4-yl)phenyl]-124-oxadiazol-5-yl}methyl)-1H-indole

SMILES

C(c1c[nH]c2c1cccc2)c1nc(-c(cc2)ccc2N2CCOCC2)no1

InChI

InChI=1S/C21H20N4O2/c1-2-4-19-18(3-1)16(14-22-19)13-20-23-21(24-27-20)15-5-7-17(8-6-15)25-9-11-26-12-10-25/h1-8,14,22H,9-13H2

InChI Key

NSNZVGUPDZQPMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27120723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.121

Distribution Coefficient, logD

4.121

Water Solubility, LogSw

-4.28

Polar Surface Area

52.542

Acid Dissociation Constant (pKa)

18.56

Base Dissociation Constant (pKb)

4.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

F373-0500 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Phosphatases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F373-0500 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F373-0500?
Check Price and Availability of F373-0500, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F373-0500 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F373-0500
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F373-0500
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F373-0500 available by request