F377-0231 Screening compound: N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide

F377-0231 Screening compound: N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide
F377-0231 Screening compound: N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F377-0231
N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F377-0231

Molecular Formula

C25H28N4O3S (C25 H28 N4 O3 S)

Compound Name

N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide

IUPAC name

N-phenyl-1-[6-(pyrrolidine-1-sulfonyl)quinolin-2-yl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1ccc(cc(cc2)S(N3CCCC3)(=O)=O)c2n1)Nc1ccccc1

InChI

InChI=1S/C25H28N4O3S/c30-25(26-21-8-2-1-3-9-21)20-7-6-14-28(18-20)24-13-10-19-17-22(11-12-23(19)27-24)33(31,32)29-15-4-5-16-29/h1-3,8-13,17,20H,4-7,14-16,18H2,(H,26,30)/t20-/m0/s1

InChI Key

KDYXOZUBODQIAM-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27120842

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.719

Distribution Coefficient, logD

3.719

Water Solubility, LogSw

-4.01

Polar Surface Area

66.587

Acid Dissociation Constant (pKa)

11.87

Base Dissociation Constant (pKb)

3.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

F377-0231 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F377-0231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F377-0231?
Check Price and Availability of F377-0231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F377-0231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F377-0231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F377-0231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F377-0231 available by request