F378-0162 Screening compound: ethyl 3,5-dimethyl-4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate

F378-0162 Screening compound: ethyl 3,5-dimethyl-4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate
F378-0162 Screening compound: ethyl 3,5-dimethyl-4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound F378-0162
ethyl 3,5-dimethyl-4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F378-0162

Molecular Formula

C13H17N3O5S (C13 H17 N3 O5 S)

Compound Name

ethyl 3,5-dimethyl-4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate

IUPAC name

ethyl 35-dimethyl-4-[(5-methyl-12-oxazol-3-yl)sulfamoyl]-1H-pyrrole-2-carboxylate

SMILES

CCOC(c1c(C)c(S(Nc2noc(C)c2)(=O)=O)c(C)[nH]1)=O

InChI

InChI=1S/C13H17N3O5S/c1-5-20-13(17)11-8(3)12(9(4)14-11)22(18,19)16-10-6-7(2)21-15-10/h6,14H,5H2,1-4H3,(H,15,16)

InChI Key

GADKFAOSVXMYLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14952327

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

327.36

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.828

Distribution Coefficient, logD

-1.055

Water Solubility, LogSw

-2.52

Polar Surface Area

94.419

Acid Dissociation Constant (pKa)

4.52

Base Dissociation Constant (pKb)

-3.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

F378-0162 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F378-0162 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F378-0162?
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What is the minimum amount of F378-0162 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F378-0162
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F378-0162
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F378-0162 available by request