F378-0183 Screening compound: ethyl 3,5-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate

F378-0183 Screening compound: ethyl 3,5-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate
F378-0183 Screening compound: ethyl 3,5-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound F378-0183
ethyl 3,5-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F378-0183

Molecular Formula

C16H17F3N2O5S (C16 H17 F3 N2 O5 S)

Compound Name

ethyl 3,5-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate

IUPAC name

ethyl 35-dimethyl-4-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1H-pyrrole-2-carboxylate

SMILES

CCOC(c1c(C)c(S(Nc(cc2)ccc2OC(F)(F)F)(=O)=O)c(C)[nH]1)=O

InChI

InChI=1S/C16H17F3N2O5S/c1-4-25-15(22)13-9(2)14(10(3)20-13)27(23,24)21-11-5-7-12(8-6-11)26-16(17,18)19/h5-8,20-21H,4H2,1-3H3

InChI Key

ZDCRWCVOVPMWEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27121006

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.38

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.952

Distribution Coefficient, logD

3.893

Water Solubility, LogSw

-3.93

Polar Surface Area

78.560

Acid Dissociation Constant (pKa)

8.24

Base Dissociation Constant (pKb)

-4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

F378-0183 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F378-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F378-0183?
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What is the minimum amount of F378-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F378-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F378-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F378-0183 available by request