F386-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-1,2,4-oxadiazole-5-carboxamide

F386-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-1,2,4-oxadiazole-5-carboxamide
F386-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F386-0286
N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F386-0286

Molecular Formula

C22H22N6O2 (C22 H22 N6 O2)

Compound Name

N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-{[4-(dimethylamino)phenyl]methyl}-3-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-124-oxadiazole-5-carboxamide

SMILES

Cc(c(-c1noc(C(NCc(cc2)ccc2N(C)C)=O)n1)c1)nn1-c1ccccc1

InChI

InChI=1S/C22H22N6O2/c1-15-19(14-28(25-15)18-7-5-4-6-8-18)20-24-22(30-26-20)21(29)23-13-16-9-11-17(12-10-16)27(2)3/h4-12,14H,13H2,1-3H3,(H,23,29)

InChI Key

JGCNUWYSCFMQKI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14952671

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.196

Distribution Coefficient, logD

3.181

Water Solubility, LogSw

-3.50

Polar Surface Area

73.844

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F386-0286 in Drug Discovery

Included in Screening Libraries

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with F386-0286 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F386-0286?
Check Price and Availability of F386-0286, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F386-0286 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F386-0286
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F386-0286
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F386-0286 available by request