F387-0184 Screening compound: 2-ethyl-3-({5-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-3,4-dihydroquinazolin-4-one

F387-0184 Screening compound: 2-ethyl-3-({5-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-3,4-dihydroquinazolin-4-one
F387-0184 Screening compound: 2-ethyl-3-({5-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F387-0184
2-ethyl-3-({5-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F387-0184

Molecular Formula

C27H20N6O3 (C27 H20 N6 O3)

Compound Name

2-ethyl-3-({5-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-3,4-dihydroquinazolin-4-one

IUPAC name

2-ethyl-3-({5-[3-(5-phenyl-134-oxadiazol-2-yl)phenyl]-124-oxadiazol-3-yl}methyl)-34-dihydroquinazolin-4-one

SMILES

CCC(N1Cc2noc(-c3cc(-c4nnc(-c5ccccc5)o4)ccc3)n2)=Nc(cccc2)c2C1=O

InChI

InChI=1S/C27H20N6O3/c1-2-23-28-21-14-7-6-13-20(21)27(34)33(23)16-22-29-24(36-32-22)18-11-8-12-19(15-18)26-31-30-25(35-26)17-9-4-3-5-10-17/h3-15H,2,16H2,1H3

InChI Key

UTRUNKQYKVKDSK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27122093

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.974

Distribution Coefficient, logD

3.973

Water Solubility, LogSw

-4.26

Polar Surface Area

88.389

Acid Dissociation Constant (pKa)

20.99

Base Dissociation Constant (pKb)

3.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F387-0184 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F387-0184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F387-0184?
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What is the minimum amount of F387-0184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F387-0184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F387-0184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F387-0184 available by request