F389-0356 Screening compound: (2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

F389-0356 Screening compound: (2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
F389-0356 Screening compound: (2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F389-0356
(2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F389-0356

Molecular Formula

C27H26N2O6 (C27 H26 N2 O6)

Compound Name

(2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

IUPAC name

(2E)-N-[(3-ethoxy-4-methoxyphenyl)methyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-34-dihydro-2H-14-benzoxazine-6-carboxamide

SMILES

CCOc(cc(CNC(c(cc1)cc(NC2=O)c1O/C2=C/c(cccc1)c1OC)=O)cc1)c1OC

InChI

InChI=1S/C27H26N2O6/c1-4-34-24-13-17(9-11-23(24)33-3)16-28-26(30)19-10-12-22-20(14-19)29-27(31)25(35-22)15-18-7-5-6-8-21(18)32-2/h5-15H,4,16H2,1-3H3,(H,28,30)(H,29,31)

InChI Key

DSMSSXOQIIAZQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14952971

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.916

Distribution Coefficient, logD

3.916

Water Solubility, LogSw

-4.10

Polar Surface Area

79.692

Acid Dissociation Constant (pKa)

12.28

Base Dissociation Constant (pKb)

-2.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

F389-0356 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F389-0356 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F389-0356?
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What is the minimum amount of F389-0356 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F389-0356
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F389-0356
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F389-0356 available by request