F389-0380 Screening compound: (2E)-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

F389-0380 Screening compound: (2E)-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
F389-0380 Screening compound: (2E)-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F389-0380
(2E)-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F389-0380

Molecular Formula

C27H24N2O6 (C27 H24 N2 O6)

Compound Name

(2E)-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide

IUPAC name

(2E)-N-[1-(23-dihydro-14-benzodioxin-6-yl)ethyl]-2-[(2-methoxyphenyl)methylidene]-3-oxo-34-dihydro-2H-14-benzoxazine-6-carboxamide

SMILES

CC(c(cc1)cc2c1OCCO2)NC(c(cc1)cc(NC2=O)c1O/C2=C/c(cccc1)c1OC)=O

InChI

InChI=1S/C27H24N2O6/c1-16(17-7-10-23-24(14-17)34-12-11-33-23)28-26(30)19-8-9-22-20(13-19)29-27(31)25(35-22)15-18-5-3-4-6-21(18)32-2/h3-10,13-16H,11-12H2,1-2H3,(H,28,30)(H,29,31)/t16-/m0/s1

InChI Key

FDQOMNHDIOJUDC-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14952983

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.683

Distribution Coefficient, logD

3.683

Water Solubility, LogSw

-4.11

Polar Surface Area

79.838

Acid Dissociation Constant (pKa)

12.28

Base Dissociation Constant (pKb)

-1.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.50

F389-0380 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F389-0380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F389-0380?
Check Price and Availability of F389-0380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F389-0380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F389-0380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F389-0380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F389-0380 available by request