F393-0145 Screening compound: N-{4-methyl-5-oxo-1H,2H,4H,5H-imidazo[1,2-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide

F393-0145 Screening compound: N-{4-methyl-5-oxo-1H,2H,4H,5H-imidazo[1,2-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide
F393-0145 Screening compound: N-{4-methyl-5-oxo-1H,2H,4H,5H-imidazo[1,2-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F393-0145
N-{4-methyl-5-oxo-1H,2H,4H,5H-imidazo[1,2-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F393-0145

Molecular Formula

C19H23N5O4 (C19 H23 N5 O4)

Compound Name

N-{4-methyl-5-oxo-1H,2H,4H,5H-imidazo[1,2-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide

IUPAC name

N-{4-methyl-5-oxo-1H2H4H5H-imidazo[12-a]quinazolin-7-yl}-4-(morpholin-4-yl)-4-oxobutanamide

SMILES

CN(C1=NCCN1c(cc1)c2cc1NC(CCC(N1CCOCC1)=O)=O)C2=O

InChI

InChI=1S/C19H23N5O4/c1-22-18(27)14-12-13(2-3-15(14)24-7-6-20-19(22)24)21-16(25)4-5-17(26)23-8-10-28-11-9-23/h2-3,12H,4-11H2,1H3,(H,21,25)

InChI Key

BSZQYAPGYMZORF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14953805

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.518

Distribution Coefficient, logD

-0.939

Water Solubility, LogSw

-2.17

Polar Surface Area

76.486

Acid Dissociation Constant (pKa)

11.86

Base Dissociation Constant (pKb)

7.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.40

F393-0145 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F393-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F393-0145?
Check Price and Availability of F393-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F393-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F393-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F393-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F393-0145 available by request