F398-0375 Screening compound: 2-(3,4-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine

F398-0375 Screening compound: 2-(3,4-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine
F398-0375 Screening compound: 2-(3,4-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound F398-0375
2-(3,4-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F398-0375

Molecular Formula

C18H18N2O4S3 (C18 H18 N2 O4 S3)

Compound Name

2-(3,4-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine

IUPAC name

2-(34-dimethoxyphenyl)-5-(thiophene-2-sulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridine

SMILES

COc(ccc(-c1nc(CCN(C2)S(c3cccs3)(=O)=O)c2s1)c1)c1OC

InChI

InChI=1S/C18H18N2O4S3/c1-23-14-6-5-12(10-15(14)24-2)18-19-13-7-8-20(11-16(13)26-18)27(21,22)17-4-3-9-25-17/h3-6,9-10H,7-8,11H2,1-2H3

InChI Key

XEQJYQLLTDFPON-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27123414

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.640

Distribution Coefficient, logD

3.640

Water Solubility, LogSw

-3.94

Polar Surface Area

59.125

Acid Dissociation Constant (pKa)

26.68

Base Dissociation Constant (pKb)

1.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

F398-0375 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F398-0375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F398-0375?
Check Price and Availability of F398-0375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F398-0375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F398-0375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F398-0375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F398-0375 available by request