F402-0382 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[7,8-dimethyl-2-oxo-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

F402-0382 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[7,8-dimethyl-2-oxo-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide
F402-0382 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[7,8-dimethyl-2-oxo-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F402-0382
N-(4-chloro-2-methoxy-5-methylphenyl)-2-[7,8-dimethyl-2-oxo-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F402-0382

Molecular Formula

C25H24ClN3O3S (C25 H24 ClN3 O3 S)

Compound Name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-[7,8-dimethyl-2-oxo-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

IUPAC name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-[78-dimethyl-2-oxo-4-(thiophen-2-yl)-23-dihydro-1H-15-benzodiazepin-1-yl]acetamide

SMILES

Cc(c(C)c1)cc(N(CC(Nc(c(OC)c2)cc(C)c2Cl)=O)C(C2)=O)c1N=C2c1cccs1

InChI

InChI=1S/C25H24ClN3O3S/c1-14-8-18-21(10-15(14)2)29(25(31)12-20(27-18)23-6-5-7-33-23)13-24(30)28-19-9-16(3)17(26)11-22(19)32-4/h5-11H,12-13H2,1-4H3,(H,28,30)

InChI Key

QOTPXXJOOQJGQJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27124584

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.776

Distribution Coefficient, logD

5.772

Water Solubility, LogSw

-5.97

Polar Surface Area

55.690

Acid Dissociation Constant (pKa)

9.45

Base Dissociation Constant (pKb)

0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

F402-0382 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F402-0382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F402-0382?
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What is the minimum amount of F402-0382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F402-0382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F402-0382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F402-0382 available by request