F402-0918 Screening compound: 1-[(3-bromophenyl)methyl]-7,8-dimethyl-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

F402-0918 Screening compound: 1-[(3-bromophenyl)methyl]-7,8-dimethyl-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one
F402-0918 Screening compound: 1-[(3-bromophenyl)methyl]-7,8-dimethyl-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F402-0918
1-[(3-bromophenyl)methyl]-7,8-dimethyl-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F402-0918

Molecular Formula

C22H19BrN2OS (C22 H19 BrN2 OS)

Compound Name

1-[(3-bromophenyl)methyl]-7,8-dimethyl-4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

IUPAC name

1-[(3-bromophenyl)methyl]-78-dimethyl-4-(thiophen-2-yl)-23-dihydro-1H-15-benzodiazepin-2-one

SMILES

Cc(c(C)c1)cc(N(Cc2cccc(Br)c2)C(C2)=O)c1N=C2c1cccs1

InChI

InChI=1S/C22H19BrN2OS/c1-14-9-18-20(10-15(14)2)25(13-16-5-3-6-17(23)11-16)22(26)12-19(24-18)21-7-4-8-27-21/h3-11H,12-13H2,1-2H3

InChI Key

FBUCSNYTHKTATD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27124705

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.130

Distribution Coefficient, logD

6.130

Water Solubility, LogSw

-5.46

Polar Surface Area

25.608

Acid Dissociation Constant (pKa)

12.85

Base Dissociation Constant (pKb)

-0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F402-0918 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F402-0918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F402-0918?
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What is the minimum amount of F402-0918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F402-0918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F402-0918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F402-0918 available by request