F407-0145 Screening compound: 5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol

F407-0145 Screening compound: 5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol
F407-0145 Screening compound: 5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound F407-0145
5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F407-0145

Molecular Formula

C21H25N3O3S (C21 H25 N3 O3 S)

Compound Name

5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol

IUPAC name

5-ethyl-6-methyl-2-[({5-methyl-2-[4-(propan-2-yloxy)phenyl]-13-oxazol-4-yl}methyl)sulfanyl]pyrimidin-4-ol

SMILES

CCc(c(C)nc(SCc1c(C)oc(-c(cc2)ccc2OC(C)C)n1)n1)c1O

InChI

InChI=1S/C21H25N3O3S/c1-6-17-13(4)22-21(24-19(17)25)28-11-18-14(5)27-20(23-18)15-7-9-16(10-8-15)26-12(2)3/h7-10,12H,6,11H2,1-5H3,(H,22,24,25)

InChI Key

LKWFIMBLMDJWAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27125698

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.771

Distribution Coefficient, logD

4.739

Water Solubility, LogSw

-4.46

Polar Surface Area

59.722

Acid Dissociation Constant (pKa)

8.52

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

F407-0145 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with F407-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F407-0145?
Check Price and Availability of F407-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F407-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F407-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F407-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F407-0145 available by request