F425-0137 Screening compound: 3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

F425-0137 Screening compound: 3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one
F425-0137 Screening compound: 3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F425-0137
3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F425-0137

Molecular Formula

C22H17N5O3S2 (C22 H17 N5 O3 S2)

Compound Name

3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

IUPAC name

3-(4-ethoxyphenyl)-2-({[3-(pyridin-4-yl)-124-oxadiazol-5-yl]methyl}sulfanyl)-3H4H-thieno[32-d]pyrimidin-4-one

SMILES

CCOc(cc1)ccc1N(C1=O)C(SCc2nc(-c3ccncc3)no2)=Nc2c1scc2

InChI

InChI=1S/C22H17N5O3S2/c1-2-29-16-5-3-15(4-6-16)27-21(28)19-17(9-12-31-19)24-22(27)32-13-18-25-20(26-30-18)14-7-10-23-11-8-14/h3-12H,2,13H2,1H3

InChI Key

QOMWUEZHJNSQEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127079

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.180

Distribution Coefficient, logD

4.180

Water Solubility, LogSw

-3.99

Polar Surface Area

74.073

Acid Dissociation Constant (pKa)

29.85

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

F425-0137 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F425-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F425-0137?
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What is the minimum amount of F425-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F425-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F425-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F425-0137 available by request