F425-0185 Screening compound: 3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

F425-0185 Screening compound: 3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one
F425-0185 Screening compound: 3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F425-0185
3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F425-0185

Molecular Formula

C20H12ClN5O2S2 (C20 H12 ClN5 O2 S2)

Compound Name

3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one

IUPAC name

3-(4-chlorophenyl)-2-({[3-(pyridin-2-yl)-124-oxadiazol-5-yl]methyl}sulfanyl)-3H4H-thieno[32-d]pyrimidin-4-one

SMILES

O=C1N(c(cc2)ccc2Cl)C(SCc2nc(-c3ncccc3)no2)=Nc2c1scc2

InChI

InChI=1S/C20H12ClN5O2S2/c21-12-4-6-13(7-5-12)26-19(27)17-14(8-10-29-17)23-20(26)30-11-16-24-18(25-28-16)15-3-1-2-9-22-15/h1-10H,11H2

InChI Key

PACNWKYCQOPEHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11996632

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.93

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.279

Distribution Coefficient, logD

4.279

Water Solubility, LogSw

-4.67

Polar Surface Area

66.569

Acid Dissociation Constant (pKa)

35.59

Base Dissociation Constant (pKb)

3.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

F425-0185 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F425-0185 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F425-0185?
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What is the minimum amount of F425-0185 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F425-0185
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F425-0185
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F425-0185 available by request