F426-0220 Screening compound: 4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine

F426-0220 Screening compound: 4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine
F426-0220 Screening compound: 4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound F426-0220
4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F426-0220

Molecular Formula

C21H26N4O (C21 H26 N4 O)

Compound Name

4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine

IUPAC name

4-(3-methylphenyl)-6-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]pyrimidine

SMILES

Cc1cccc(-c2cc(N(CC3)CCC3C(N3CCCC3)=O)ncn2)c1

InChI

InChI=1S/C21H26N4O/c1-16-5-4-6-18(13-16)19-14-20(23-15-22-19)24-11-7-17(8-12-24)21(26)25-9-2-3-10-25/h4-6,13-15,17H,2-3,7-12H2,1H3

InChI Key

YDKLNWIZUQUFJA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127259

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.163

Distribution Coefficient, logD

4.157

Water Solubility, LogSw

-4.22

Polar Surface Area

39.707

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

5.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

F426-0220 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F426-0220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F426-0220?
Check Price and Availability of F426-0220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F426-0220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F426-0220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F426-0220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F426-0220 available by request