F426-0263 Screening compound: N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide

F426-0263 Screening compound: N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide
F426-0263 Screening compound: N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F426-0263
N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F426-0263

Molecular Formula

C28H35N5O (C28 H35 N5 O)

Compound Name

N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide

IUPAC name

N-{2-[benzyl(ethyl)amino]ethyl}-1-[6-(3-methylphenyl)pyrimidin-4-yl]piperidine-4-carboxamide

SMILES

CCN(CCNC(C(CC1)CCN1c1ncnc(-c2cc(C)ccc2)c1)=O)Cc1ccccc1

InChI

InChI=1S/C28H35N5O/c1-3-32(20-23-9-5-4-6-10-23)17-14-29-28(34)24-12-15-33(16-13-24)27-19-26(30-21-31-27)25-11-7-8-22(2)18-25/h4-11,18-19,21,24H,3,12-17,20H2,1-2H3,(H,29,34)

InChI Key

PDSVVVWFVVRKBV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127286

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.930

Distribution Coefficient, logD

4.079

Water Solubility, LogSw

-4.53

Polar Surface Area

50.634

Acid Dissociation Constant (pKa)

13.35

Base Dissociation Constant (pKb)

8.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

F426-0263 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Nervous system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with F426-0263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F426-0263?
Check Price and Availability of F426-0263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F426-0263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F426-0263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F426-0263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F426-0263 available by request