F426-0403 Screening compound: N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

F426-0403 Screening compound: N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide
F426-0403 Screening compound: N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F426-0403
N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F426-0403

Molecular Formula

C19H21FN4O (C19 H21 FN4 O)

Compound Name

N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

IUPAC name

N-cyclopropyl-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1cc(-c2cccc(F)c2)ncn1)NC1CC1

InChI

InChI=1S/C19H21FN4O/c20-15-3-1-2-14(10-15)17-11-18(22-12-21-17)24-8-6-13(7-9-24)19(25)23-16-4-5-16/h1-3,10-13,16H,4-9H2,(H,23,25)

InChI Key

WUBMVHSCDXTTMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127383

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.329

Distribution Coefficient, logD

3.327

Water Solubility, LogSw

-3.43

Polar Surface Area

47.162

Acid Dissociation Constant (pKa)

13.20

Base Dissociation Constant (pKb)

5.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

F426-0403 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Agro:
  • Agro
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F426-0403 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F426-0403?
Check Price and Availability of F426-0403, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F426-0403 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F426-0403
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F426-0403
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F426-0403 available by request