F426-0405 Screening compound: N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

F426-0405 Screening compound: N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide
F426-0405 Screening compound: N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F426-0405
N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F426-0405

Molecular Formula

C21H27FN4O2 (C21 H27 FN4 O2)

Compound Name

N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

IUPAC name

N-(3-ethoxypropyl)-1-[6-(3-fluorophenyl)pyrimidin-4-yl]piperidine-4-carboxamide

SMILES

CCOCCCNC(C(CC1)CCN1c1cc(-c2cccc(F)c2)ncn1)=O

InChI

InChI=1S/C21H27FN4O2/c1-2-28-12-4-9-23-21(27)16-7-10-26(11-8-16)20-14-19(24-15-25-20)17-5-3-6-18(22)13-17/h3,5-6,13-16H,2,4,7-12H2,1H3,(H,23,27)

InChI Key

UVTKDDKGJXMHEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27127385

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.453

Distribution Coefficient, logD

3.451

Water Solubility, LogSw

-3.60

Polar Surface Area

55.196

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

F426-0405 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F426-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F426-0405?
Check Price and Availability of F426-0405, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F426-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F426-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F426-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F426-0405 available by request