F428-0608 Screening compound: 3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine

F428-0608 Screening compound: 3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine
F428-0608 Screening compound: 3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F428-0608
3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F428-0608

Molecular Formula

C24H32N6O3 (C24 H32 N6 O3)

Compound Name

3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine

IUPAC name

3-{4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-(piperidin-1-yl)pyridazine

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1N1CCCCC1)N(CC1)CCN1C(c1ccco1)=O

InChI

InChI=1S/C24H32N6O3/c31-23(29-14-16-30(17-15-29)24(32)20-5-4-18-33-20)19-8-12-28(13-9-19)22-7-6-21(25-26-22)27-10-2-1-3-11-27/h4-7,18-19H,1-3,8-17H2

InChI Key

PZEYLENXWCSKTI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14954264

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.358

Distribution Coefficient, logD

2.355

Water Solubility, LogSw

-2.41

Polar Surface Area

69.496

Acid Dissociation Constant (pKa)

22.96

Base Dissociation Constant (pKb)

7.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.30

F428-0608 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F428-0608 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F428-0608?
Check Price and Availability of F428-0608, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F428-0608 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F428-0608
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F428-0608
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F428-0608 available by request