F430-1852 Screening compound: 3,4-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide

F430-1852 Screening compound: 3,4-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide
F430-1852 Screening compound: 3,4-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F430-1852
3,4-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F430-1852

Molecular Formula

C23H22F2N4O4 (C23 H22 F2 N4 O4)

Compound Name

3,4-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide

IUPAC name

34-difluoro-N-[(E)-N-[(pyridin-4-yl)methyl]-N'-(345-trimethoxyphenyl)carbamimidoyl]benzamide

SMILES

COc1cc(/N=C(\NCc2ccncc2)/NC(c(cc2)cc(F)c2F)=O)cc(OC)c1OC

InChI

InChI=1S/C23H22F2N4O4/c1-31-19-11-16(12-20(32-2)21(19)33-3)28-23(27-13-14-6-8-26-9-7-14)29-22(30)15-4-5-17(24)18(25)10-15/h4-12H,13H2,1-3H3,(H2,27,28,29,30)

InChI Key

LIBWXJRREPPZTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14954339

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.641

Distribution Coefficient, logD

2.196

Water Solubility, LogSw

-3.05

Polar Surface Area

74.257

Acid Dissociation Constant (pKa)

9.75

Base Dissociation Constant (pKb)

7.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

F430-1852 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with F430-1852 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F430-1852?
Check Price and Availability of F430-1852, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F430-1852 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F430-1852
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F430-1852
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F430-1852 available by request