F434-0491 Screening compound: N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

F434-0491 Screening compound: N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide
F434-0491 Screening compound: N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F434-0491
N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F434-0491

Molecular Formula

C18H15BrFN3O2 (C18 H15 BrFN3 O2)

Compound Name

N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

IUPAC name

N-[(5-bromo-2-methoxyphenyl)methyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

SMILES

COc(cc1)c(CNC(c2cn(-c(cc3)ccc3F)nc2)=O)cc1Br

InChI

InChI=1S/C18H15BrFN3O2/c1-25-17-7-2-14(19)8-12(17)9-21-18(24)13-10-22-23(11-13)16-5-3-15(20)4-6-16/h2-8,10-11H,9H2,1H3,(H,21,24)

InChI Key

CXUFFAKMYCIGRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27128759

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.24

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.731

Distribution Coefficient, logD

3.731

Water Solubility, LogSw

-3.96

Polar Surface Area

46.640

Acid Dissociation Constant (pKa)

12.46

Base Dissociation Constant (pKb)

-0.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

F434-0491 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F434-0491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F434-0491?
Check Price and Availability of F434-0491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F434-0491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F434-0491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F434-0491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F434-0491 available by request