F443-0091 Screening compound: 4-{3-[(4-chlorophenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}-N-(2,5-difluorophenyl)benzamide

F443-0091 Screening compound: 4-{3-[(4-chlorophenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}-N-(2,5-difluorophenyl)benzamide
F443-0091 Screening compound: 4-{3-[(4-chlorophenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}-N-(2,5-difluorophenyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F443-0091
4-{3-[(4-chlorophenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}-N-(2,5-difluorophenyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F443-0091

Molecular Formula

C24H16ClF2N3O3 (C24 H16 ClF2 N3 O3)

Compound Name

4-{3-[(4-chlorophenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}-N-(2,5-difluorophenyl)benzamide

IUPAC name

4-{3-[(4-chlorophenyl)methoxy]-6-oxo-16-dihydropyridazin-1-yl}-N-(25-difluorophenyl)benzamide

SMILES

O=C(c(cc1)ccc1N(C(C=C1)=O)N=C1OCc(cc1)ccc1Cl)Nc(cc(cc1)F)c1F

InChI

InChI=1S/C24H16ClF2N3O3/c25-17-5-1-15(2-6-17)14-33-22-11-12-23(31)30(29-22)19-8-3-16(4-9-19)24(32)28-21-13-18(26)7-10-20(21)27/h1-13H,14H2,(H,28,32)

InChI Key

DNKIFXPOOMDDBE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27129042

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.86

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.967

Distribution Coefficient, logD

4.583

Water Solubility, LogSw

-5.36

Polar Surface Area

58.106

Acid Dissociation Constant (pKa)

7.25

Base Dissociation Constant (pKb)

-0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

F443-0091 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

Targeted Diversity Library (40567 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F443-0091 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F443-0091?
Check Price and Availability of F443-0091, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F443-0091 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F443-0091
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F443-0091
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F443-0091 available by request