F443-0280 Screening compound: N-(2,5-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}benzamide

F443-0280 Screening compound: N-(2,5-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}benzamide
F443-0280 Screening compound: N-(2,5-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F443-0280
N-(2,5-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F443-0280

Molecular Formula

C29H29N3O5 (C29 H29 N3 O5)

Compound Name

N-(2,5-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-1,6-dihydropyridazin-1-yl}benzamide

IUPAC name

N-(25-diethoxyphenyl)-4-{3-[(3-methylphenyl)methoxy]-6-oxo-16-dihydropyridazin-1-yl}benzamide

SMILES

CCOc(cc1)cc(NC(c(cc2)ccc2N(C(C=C2)=O)N=C2OCc2cc(C)ccc2)=O)c1OCC

InChI

InChI=1S/C29H29N3O5/c1-4-35-24-13-14-26(36-5-2)25(18-24)30-29(34)22-9-11-23(12-10-22)32-28(33)16-15-27(31-32)37-19-21-8-6-7-20(3)17-21/h6-18H,4-5,19H2,1-3H3,(H,30,34)

InChI Key

BVOHMXXXAAGMKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27129078

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.394

Distribution Coefficient, logD

5.368

Water Solubility, LogSw

-5.43

Polar Surface Area

72.440

Acid Dissociation Constant (pKa)

8.61

Base Dissociation Constant (pKb)

-0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.70

F443-0280 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F443-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F443-0280?
Check Price and Availability of F443-0280, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F443-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F443-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F443-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F443-0280 available by request