F449-3553 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]acetamide

F449-3553 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]acetamide
F449-3553 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F449-3553
2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F449-3553

Molecular Formula

C25H33N7O2S (C25 H33 N7 O2 S)

Compound Name

2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]acetamide

IUPAC name

2-{[5-(tert-butylamino)-6-(4-methylphenyl)imidazo[21-b][134]thiadiazol-2-yl](methyl)amino}-N-[2-(35-dimethyl-12-oxazol-4-yl)ethyl]acetamide

SMILES

CC(C)(C)Nc1c(-c2ccc(C)cc2)nc2sc(N(C)CC(NCCc3c(C)onc3C)=O)nn12

InChI

InChI=1S/C25H33N7O2S/c1-15-8-10-18(11-9-15)21-22(28-25(4,5)6)32-23(27-21)35-24(29-32)31(7)14-20(33)26-13-12-19-16(2)30-34-17(19)3/h8-11,28H,12-14H2,1-7H3,(H,26,33)

InChI Key

GUQHJIYLHNEAEO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27129913

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.025

Distribution Coefficient, logD

4.025

Water Solubility, LogSw

-4.06

Polar Surface Area

79.633

Acid Dissociation Constant (pKa)

14.86

Base Dissociation Constant (pKb)

4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

References: we are preparing a list of scientific research reports with F449-3553 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F449-3553?
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What is the minimum amount of F449-3553 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F449-3553
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F449-3553
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F449-3553 available by request