F452-0046 Screening compound: 1,4-bis(3,4-dimethoxyphenyl)piperidine-2,6-dione

F452-0046 Screening compound: 1,4-bis(3,4-dimethoxyphenyl)piperidine-2,6-dione
F452-0046 Screening compound: 1,4-bis(3,4-dimethoxyphenyl)piperidine-2,6-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound F452-0046
1,4-bis(3,4-dimethoxyphenyl)piperidine-2,6-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F452-0046

Molecular Formula

C21H23NO6 (C21 H23 NO6)

Compound Name

1,4-bis(3,4-dimethoxyphenyl)piperidine-2,6-dione

IUPAC name

14-bis(34-dimethoxyphenyl)piperidine-26-dione

SMILES

COc(ccc(C(CC(N1c(cc2)cc(OC)c2OC)=O)CC1=O)c1)c1OC

InChI

InChI=1S/C21H23NO6/c1-25-16-7-5-13(9-18(16)27-3)14-10-20(23)22(21(24)11-14)15-6-8-17(26-2)19(12-15)28-4/h5-9,12,14H,10-11H2,1-4H3

InChI Key

RBXXHFNBBOYPKK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27130081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.679

Distribution Coefficient, logD

1.679

Water Solubility, LogSw

-2.08

Polar Surface Area

59.591

Acid Dissociation Constant (pKa)

16.72

Base Dissociation Constant (pKb)

-1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F452-0046 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with F452-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F452-0046?
Check Price and Availability of F452-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F452-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F452-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F452-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F452-0046 available by request