F453-0268 Screening compound: N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H,5H,6H,7H,8H,9H-pyrazolo[3,2-b]quinazoline-3-carboxamide

F453-0268 Screening compound: N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H,5H,6H,7H,8H,9H-pyrazolo[3,2-b]quinazoline-3-carboxamide
F453-0268 Screening compound: N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H,5H,6H,7H,8H,9H-pyrazolo[3,2-b]quinazoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F453-0268
N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H,5H,6H,7H,8H,9H-pyrazolo[3,2-b]quinazoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F453-0268

Molecular Formula

C25H24N4O2 (C25 H24 N4 O2)

Compound Name

N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H,5H,6H,7H,8H,9H-pyrazolo[3,2-b]quinazoline-3-carboxamide

IUPAC name

N-(2-methylphenyl)-9-(4-methylphenyl)-8-oxo-4H5H6H7H8H9H-pyrazolo[32-b]quinazoline-3-carboxamide

SMILES

Cc1ccc(C2n3ncc(C(Nc4c(C)cccc4)=O)c3NC(CCC3)=C2C3=O)cc1

InChI

InChI=1S/C25H24N4O2/c1-15-10-12-17(13-11-15)23-22-20(8-5-9-21(22)30)27-24-18(14-26-29(23)24)25(31)28-19-7-4-3-6-16(19)2/h3-4,6-7,10-14,23,27H,5,8-9H2,1-2H3,(H,28,31)/t23-/m0/s1

InChI Key

MHENPUFGOJMOMY-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27130216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.187

Distribution Coefficient, logD

4.069

Water Solubility, LogSw

-4.18

Polar Surface Area

60.124

Acid Dissociation Constant (pKa)

7.90

Base Dissociation Constant (pKb)

-2.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

F453-0268 in Drug Discovery

Included in Screening Libraries

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with F453-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F453-0268?
Check Price and Availability of F453-0268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F453-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F453-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F453-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F453-0268 available by request