F463-0487 Screening compound: 1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-N~4~-(2-furylmethyl)-4-piperidinecarboxamide

F463-0487 Screening compound: 1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-N~4~-(2-furylmethyl)-4-piperidinecarboxamide
F463-0487 Screening compound: 1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-N~4~-(2-furylmethyl)-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F463-0487
1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-N~4~-(2-furylmethyl)-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F463-0487

Molecular Formula

C22H23N5O2S (C22 H23 N5 O2 S)

Compound Name

1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-N~4~-(2-furylmethyl)-4-piperidinecarboxamide

IUPAC name

1-{1113-dimethyl-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)35911-hexaen-6-yl}-N-[(furan-2-yl)methyl]piperidine-4-carboxamide

SMILES

Cc1c(c2ncnc(N(CC3)CCC3C(NCc3ccco3)=O)c2s2)c2nc(C)c1

InChI

InChI=1S/C22H23N5O2S/c1-13-10-14(2)26-22-17(13)18-19(30-22)20(25-12-24-18)27-7-5-15(6-8-27)21(28)23-11-16-4-3-9-29-16/h3-4,9-10,12,15H,5-8,11H2,1-2H3,(H,23,28)

InChI Key

JJXLWJKKNJZOTA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14955349

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.030

Distribution Coefficient, logD

3.983

Water Solubility, LogSw

-4.13

Polar Surface Area

65.608

Acid Dissociation Constant (pKa)

12.38

Base Dissociation Constant (pKb)

6.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

F463-0487 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others
  • Others

References: we are preparing a list of scientific research reports with F463-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F463-0487?
Check Price and Availability of F463-0487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F463-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F463-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F463-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F463-0487 available by request