F463-0557 Screening compound: [1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-4-piperidyl][4-(2-pyridyl)piperazino]methanone

F463-0557 Screening compound: [1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-4-piperidyl][4-(2-pyridyl)piperazino]methanone
F463-0557 Screening compound: [1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-4-piperidyl][4-(2-pyridyl)piperazino]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound F463-0557
[1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-4-piperidyl][4-(2-pyridyl)piperazino]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F463-0557

Molecular Formula

C26H29N7OS (C26 H29 N7 OS)

Compound Name

[1-(7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-4-piperidyl][4-(2-pyridyl)piperazino]methanone

IUPAC name

1113-dimethyl-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)35911-hexaene

SMILES

Cc1c(c2ncnc(N(CC3)CCC3C(N(CC3)CCN3c3ncccc3)=O)c2s2)c2nc(C)c1

InChI

InChI=1S/C26H29N7OS/c1-17-15-18(2)30-25-21(17)22-23(35-25)24(29-16-28-22)32-9-6-19(7-10-32)26(34)33-13-11-31(12-14-33)20-5-3-4-8-27-20/h3-5,8,15-16,19H,6-7,9-14H2,1-2H3

InChI Key

HHQBCWHBILAVPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14955373

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.63

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.496

Distribution Coefficient, logD

4.449

Water Solubility, LogSw

-4.45

Polar Surface Area

61.866

Acid Dissociation Constant (pKa)

21.22

Base Dissociation Constant (pKb)

6.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

F463-0557 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F463-0557 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F463-0557?
Check Price and Availability of F463-0557, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F463-0557 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F463-0557
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F463-0557
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F463-0557 available by request