F470-1075 Screening compound: N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

F470-1075 Screening compound: N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide
F470-1075 Screening compound: N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F470-1075
N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F470-1075

Molecular Formula

C22H28N6O5 (C22 H28 N6 O5)

Compound Name

N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

IUPAC name

N-(butan-2-yl)-4-cyclopropyl-2-{[(2-methoxyethyl)carbamoyl]methyl}-15-dioxo-1H2H4H5H-[124]triazolo[43-a]quinazoline-8-carboxamide

SMILES

CCC(C)NC(c(cc1)cc(N2C(N3C4CC4)=NN(CC(NCCOC)=O)C2=O)c1C3=O)=O

InChI

InChI=1S/C22H28N6O5/c1-4-13(2)24-19(30)14-5-8-16-17(11-14)28-21(27(20(16)31)15-6-7-15)25-26(22(28)32)12-18(29)23-9-10-33-3/h5,8,11,13,15H,4,6-7,9-10,12H2,1-3H3,(H,23,29)(H,24,30)/t13-/m0/s1

InChI Key

NPWYJULHGWTSPB-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD27131961

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.294

Distribution Coefficient, logD

0.294

Water Solubility, LogSw

-2.38

Polar Surface Area

104.541

Acid Dissociation Constant (pKa)

14.12

Base Dissociation Constant (pKb)

4.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

F470-1075 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F470-1075 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F470-1075?
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What is the minimum amount of F470-1075 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F470-1075
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F470-1075
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F470-1075 available by request