F471-0759 Screening compound: N-cyclopentyl-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-methyl-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

F471-0759 Screening compound: N-cyclopentyl-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-methyl-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide
F471-0759 Screening compound: N-cyclopentyl-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-methyl-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F471-0759
N-cyclopentyl-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-methyl-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F471-0759

Molecular Formula

C26H27N5O4 (C26 H27 N5 O4)

Compound Name

N-cyclopentyl-2-[2-(2,4-dimethylphenyl)-2-oxoethyl]-4-methyl-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazoline-8-carboxamide

IUPAC name

N-cyclopentyl-2-[2-(24-dimethylphenyl)-2-oxoethyl]-4-methyl-15-dioxo-1H2H4H5H-[124]triazolo[43-a]quinazoline-8-carboxamide

SMILES

Cc(cc1)cc(C)c1C(CN(C(N1c2c3ccc(C(NC4CCCC4)=O)c2)=O)N=C1N(C)C3=O)=O

InChI

InChI=1S/C26H27N5O4/c1-15-8-10-19(16(2)12-15)22(32)14-30-26(35)31-21-13-17(23(33)27-18-6-4-5-7-18)9-11-20(21)24(34)29(3)25(31)28-30/h8-13,18H,4-7,14H2,1-3H3,(H,27,33)

InChI Key

YQMNIVXRTVVUNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27132362

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.143

Distribution Coefficient, logD

3.143

Water Solubility, LogSw

-3.39

Polar Surface Area

85.724

Acid Dissociation Constant (pKa)

14.52

Base Dissociation Constant (pKb)

-2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

F471-0759 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic
  • Epigenetic

References: we are preparing a list of scientific research reports with F471-0759 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F471-0759?
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What is the minimum amount of F471-0759 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F471-0759
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F471-0759
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F471-0759 available by request