F473-2368 Screening compound: 8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

F473-2368 Screening compound: 8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane
F473-2368 Screening compound: 8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound F473-2368
8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F473-2368

Molecular Formula

C25H25FN2O4 (C25 H25 FN2 O4)

Compound Name

8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[4-ethoxy-2-(4-fluorophenyl)quinoline-6-carbonyl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

CCOc(c1c2)cc(-c(cc3)ccc3F)nc1ccc2C(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C25H25FN2O4/c1-2-30-23-16-22(17-3-6-19(26)7-4-17)27-21-8-5-18(15-20(21)23)24(29)28-11-9-25(10-12-28)31-13-14-32-25/h3-8,15-16H,2,9-14H2,1H3

InChI Key

BBMGWGANBGWKCH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14955775

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.960

Distribution Coefficient, logD

3.960

Water Solubility, LogSw

-4.00

Polar Surface Area

46.593

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

3.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

F473-2368 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with F473-2368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F473-2368?
Check Price and Availability of F473-2368, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F473-2368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F473-2368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F473-2368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F473-2368 available by request