F487-0139 Screening compound: 4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole

F487-0139 Screening compound: 4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole
F487-0139 Screening compound: 4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound F487-0139
4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F487-0139

Molecular Formula

C20H13F4N3S (C20 H13 F4 N3 S)

Compound Name

4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole

IUPAC name

4-(4-fluorophenyl)-2-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-13-thiazole

SMILES

Cc(cc1)ccc1-c(cc1C(F)(F)F)nn1-c1nc(-c(cc2)ccc2F)cs1

InChI

InChI=1S/C20H13F4N3S/c1-12-2-4-13(5-3-12)16-10-18(20(22,23)24)27(26-16)19-25-17(11-28-19)14-6-8-15(21)9-7-14/h2-11H,1H3

InChI Key

MUPFISJQSOURDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06240014

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.4

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.032

Distribution Coefficient, logD

7.032

Water Solubility, LogSw

-5.92

Polar Surface Area

22.610

Acid Dissociation Constant (pKa)

28.37

Base Dissociation Constant (pKb)

0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

F487-0139 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with F487-0139 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F487-0139?
Check Price and Availability of F487-0139, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F487-0139 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F487-0139
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F487-0139
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F487-0139 available by request