F501-0580 Screening compound: N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-1,3,4-thiadiazole-2-carboxamide

F501-0580 Screening compound: N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-1,3,4-thiadiazole-2-carboxamide
F501-0580 Screening compound: N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F501-0580
N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F501-0580

Molecular Formula

C19H19N5O2S (C19 H19 N5 O2 S)

Compound Name

N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-phenyl-5-(3-{[(pyridin-2-yl)methyl]carbamoyl}propyl)-134-thiadiazole-2-carboxamide

SMILES

O=C(CCCc1nnc(C(Nc2ccccc2)=O)s1)NCc1ncccc1

InChI

InChI=1S/C19H19N5O2S/c25-16(21-13-15-9-4-5-12-20-15)10-6-11-17-23-24-19(27-17)18(26)22-14-7-2-1-3-8-14/h1-5,7-9,12H,6,10-11,13H2,(H,21,25)(H,22,26)

InChI Key

PEDXIJKGJOAZDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14957009

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.728

Distribution Coefficient, logD

1.728

Water Solubility, LogSw

-2.30

Polar Surface Area

81.072

Acid Dissociation Constant (pKa)

11.40

Base Dissociation Constant (pKb)

4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

F501-0580 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F501-0580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F501-0580?
Check Price and Availability of F501-0580, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F501-0580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F501-0580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F501-0580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F501-0580 available by request