F529-0028 Screening compound: 7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

F529-0028 Screening compound: 7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
F529-0028 Screening compound: 7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F529-0028
7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F529-0028

Molecular Formula

C23H21N5O3S (C23 H21 N5 O3 S)

Compound Name

7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

IUPAC name

7-[4-(2-phenoxyacetyl)piperazin-1-yl]-2-phenyl-5H-[134]thiadiazolo[32-a]pyrimidin-5-one

SMILES

O=C(COc1ccccc1)N(CC1)CCN1C(N=C1SC(c2ccccc2)=NN11)=CC1=O

InChI

InChI=1S/C23H21N5O3S/c29-20-15-19(24-23-28(20)25-22(32-23)17-7-3-1-4-8-17)26-11-13-27(14-12-26)21(30)16-31-18-9-5-2-6-10-18/h1-10,15H,11-14,16H2

InChI Key

NAUCPWVXERWDHY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14958075

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.360

Distribution Coefficient, logD

2.352

Water Solubility, LogSw

-2.52

Polar Surface Area

64.796

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

5.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

F529-0028 in Drug Discovery

Included in Screening Libraries

Integrin Receptors Targeted library (1715 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Immune system
Targets:
  • Others
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F529-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F529-0028?
Check Price and Availability of F529-0028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F529-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F529-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F529-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F529-0028 available by request