F531-0156 Screening compound: (2,4-dimethyl-1,3-thiazol-5-yl){4-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]piperazino}methanone

F531-0156 Screening compound: (2,4-dimethyl-1,3-thiazol-5-yl){4-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]piperazino}methanone
F531-0156 Screening compound: (2,4-dimethyl-1,3-thiazol-5-yl){4-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]piperazino}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound F531-0156
(2,4-dimethyl-1,3-thiazol-5-yl){4-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]piperazino}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F531-0156

Molecular Formula

C20H23N5O2S (C20 H23 N5 O2 S)

Compound Name

(2,4-dimethyl-1,3-thiazol-5-yl){4-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]piperazino}methanone

IUPAC name

1-(24-dimethyl-13-thiazole-5-carbonyl)-4-[4-(5-ethyl-124-oxadiazol-3-yl)phenyl]piperazine

SMILES

CCc1nc(-c(cc2)ccc2N(CC2)CCN2C(c2c(C)nc(C)s2)=O)no1

InChI

InChI=1S/C20H23N5O2S/c1-4-17-22-19(23-27-17)15-5-7-16(8-6-15)24-9-11-25(12-10-24)20(26)18-13(2)21-14(3)28-18/h5-8H,4,9-12H2,1-3H3

InChI Key

BWWZGAHDTALZRG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14958226

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.865

Distribution Coefficient, logD

3.865

Water Solubility, LogSw

-3.90

Polar Surface Area

61.879

Acid Dissociation Constant (pKa)

28.46

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

F531-0156 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F531-0156 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F531-0156?
Check Price and Availability of F531-0156, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F531-0156 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F531-0156
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F531-0156
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F531-0156 available by request