F532-0227 Screening compound: 1-{4-[5-(2,4-dimethylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-3-propylurea

F532-0227 Screening compound: 1-{4-[5-(2,4-dimethylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-3-propylurea
F532-0227 Screening compound: 1-{4-[5-(2,4-dimethylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-3-propylurea alternative view

Chemical Structure Depiction of ChemDiv screening compound F532-0227
1-{4-[5-(2,4-dimethylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-3-propylurea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F532-0227

Molecular Formula

C20H22N4O2 (C20 H22 N4 O2)

Compound Name

1-{4-[5-(2,4-dimethylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-3-propylurea

IUPAC name

1-{4-[5-(24-dimethylphenyl)-124-oxadiazol-3-yl]phenyl}-3-propylurea

SMILES

CCCNC(Nc(cc1)ccc1-c1noc(-c2c(C)cc(C)cc2)n1)=O

InChI

InChI=1S/C20H22N4O2/c1-4-11-21-20(25)22-16-8-6-15(7-9-16)18-23-19(26-24-18)17-10-5-13(2)12-14(17)3/h5-10,12H,4,11H2,1-3H3,(H2,21,22,25)

InChI Key

COHCBEPBNADQET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27172958

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.190

Distribution Coefficient, logD

5.190

Water Solubility, LogSw

-4.92

Polar Surface Area

65.382

Acid Dissociation Constant (pKa)

14.19

Base Dissociation Constant (pKb)

-0.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F532-0227 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F532-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F532-0227?
Check Price and Availability of F532-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F532-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F532-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F532-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F532-0227 available by request