F540-0157 Screening compound: 4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

F540-0157 Screening compound: 4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide
F540-0157 Screening compound: 4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F540-0157
4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F540-0157

Molecular Formula

C16H15F3N2O3S2 (C16 H15 F3 N2 O3 S2)

Compound Name

4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

IUPAC name

4-(pyrrolidine-1-carbonyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

SMILES

O=C(c1csc(S(Nc2ccc(C(F)(F)F)cc2)(=O)=O)c1)N1CCCC1

InChI

InChI=1S/C16H15F3N2O3S2/c17-16(18,19)12-3-5-13(6-4-12)20-26(23,24)14-9-11(10-25-14)15(22)21-7-1-2-8-21/h3-6,9-10,20H,1-2,7-8H2

InChI Key

JLUKOAFDVPAQFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27174125

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.563

Distribution Coefficient, logD

3.559

Water Solubility, LogSw

-3.88

Polar Surface Area

58.921

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

-5.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

F540-0157 in Drug Discovery

Included in Screening Libraries

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F540-0157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F540-0157?
Check Price and Availability of F540-0157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F540-0157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F540-0157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F540-0157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F540-0157 available by request